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initially benzoate is ligated to CoASH to kind the higher-Vitality benzoyl-CoA thioester. This reaction is catalyzed through the HXM-A and HXM-B medium-chain acid:CoA ligases and needs Vitality in the form of ATP. ... The benzoyl-CoA is then conjugated to glycine by GLYAT to variety hippuric acid, releasing CoASH. In combination with the elements